Search on:
ANAPHYLATOXINS
Descriptors Found:
1
Displaying:
1 .. 1
1 / 1
DeCS
Descriptor
English
:
Anaphylatoxins
Descriptor
Spanish
:
Anafilatoxinas
Descriptor
Portuguese
:
Anafilatoxinas
Synonyms
English
:
Anaphylatoxin
Tree Number:
D12.776.124.486.274.024
Definition
English
:
Serum
peptides
derived from certain cleaved COMPLEMENT
PROTEINS
during
COMPLEMENT ACTIVATION
. They induce smooth
MUSCLE CONTRACTION
; mast cell
HISTAMINE RELEASE
;
PLATELET AGGREGATION
; and act as mediators of the local inflammatory process. The order of
anaphylatoxin
activity from the strongest to the weakest is C5a, C3a, C4a, and C5a des-arginine.
Pharmacological Action:
Immunologic Factors
History Note
English
:
90(77); was see under PEPTIDES 1977-89
Allowable Qualifiers
English
:
AD
administration & dosage
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
RE
radiation effects
SE
secretion
TU
therapeutic use
UR
urine
Record Number:
27941
Unique Identifier:
D000706
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS