Search on: DYNORPHINS 
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Descriptor English:   Dynorphins 
Descriptor Spanish:   Dinorfinas 
Descriptor Portuguese:   Dinorfinas 
Synonyms English:   Dynorphin
Dynorphin (1-17)
Dynorphin A
Dynorphin A (1-17)  
Tree Number:   D12.644.400.575.180
D12.776.631.650.575.180
Definition English:   A class of opioid peptides including dynorphin A, dynorphin B, and smaller fragments of these peptides. Dynorphins prefer kappa-opioid receptors (RECEPTORS, OPIOID, KAPPA) and have been shown to play a role as central nervous system transmitters. 
Pharmacological Action:   Neurotransmitter Agents
 
See Related English:   Receptors, Opioid, kappa
 
History Note English:   95; was DYNORPHIN 1985-94 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UR urine  
Record Number:   22432 
Unique Identifier:   D004399 

Occurrence in VHL:
 

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