Search on: C-ANCA 
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Descriptor English:   Antibodies, Antineutrophil Cytoplasmic 
Descriptor Spanish:   Anticuerpos Anticitoplasma de Neutrófilos 
Descriptor Portuguese:   Anticorpos Anticitoplasma de Neutrófilos 
Synonyms English:   Anti-Neutrophil Cytoplasmic Antibodies
Anti-Neutrophil Cytoplasmic Antibody
Antineutrophil Cytoplasmic Antibody
Anti Neutrophil Cytoplasmic Antibodies
Anti Neutrophil Cytoplasmic Antibody
Antibodies, Anti-Neutrophil Cytoplasmic
Antibody, Anti-Neutrophil Cytoplasmic
Antibody, Antineutrophil Cytoplasmic
Cytoplasmic Antibodies, Anti-Neutrophil
Cytoplasmic Antibodies, Antineutrophil
Cytoplasmic Antibody, Anti-Neutrophil
Cytoplasmic Antibody, Antineutrophil
c ANCA
p ANCA
ANCA
c-ANCA
p-ANCA
Antineutrophil Cytoplasmic Antibodies  
Tree Number:   D12.776.124.486.485.114.323.190
D12.776.124.790.651.114.323.190
D12.776.377.715.548.114.323.190
D23.101.050
Definition English:   Autoantibodies directed against cytoplasmic constituents of POLYMORPHONUCLEAR LEUKOCYTES and/or MONOCYTES. They are used as specific markers for GRANULOMATOSIS WITH POLYANGIITIS and other diseases, though their pathophysiological role is not clear. ANCA are routinely detected by indirect immunofluorescence with three different patterns: c-ANCA (cytoplasmic), p-ANCA (perinuclear), and atypical ANCA. 
Indexing Annotation English:   do not coordinate with ANTIBODY FORMATION for /biosyn;
Pharmacological Action:   Immunologic Factors
 
History Note English:   97; was C-ANCA (NM) 1991-96 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis BI biosynthesis
BL blood CF cerebrospinal fluid
CH chemistry CL classification
CT contraindications DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PD pharmacology PH physiology
PO poisoning RE radiation effects
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   33077 
Unique Identifier:   D019268 

Occurrence in VHL:
 

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