Search on: BETA-MANNOSIDASE 
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Descriptor English:   beta-Mannosidase 
Descriptor Spanish:   beta-Manosidasa 
Descriptor Portuguese:   beta-Manosidase 
Synonyms English:   beta-Mannanase
manA protein (beta-Mannosidase)
beta D Mannosidase
beta Mannanase
beta Mannosidase
beta-D-Mannosidase  
Tree Number:   D08.811.277.450.625.750
Definition English:   An enzyme that catalyzes the hydrolysis of terminal, non-reducing beta-D-mannose residues in beta-D-mannosides. The enzyme plays a role in the lysosomal degradation of the N-glycosylprotein glycans. Defects in the lysosomal form of the enzyme in humans result in a buildup of mannoside intermediate metabolites and the disease BETA-MANNOSIDOSIS. 
Indexing Annotation English:   /defic: consider also BETA-MANNOSIDOSIS
See Related English:   beta-Mannosidosis
 
History Note English:   2004; use BETA-MANNOSIDASE (NM) 1980-2003 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   38164 
Unique Identifier:   D044902 

Occurrence in VHL:
 

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