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DeCS
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Descriptor English:
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alpha-Mannosidase
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Descriptor Spanish:
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alfa-Manosidasa
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Descriptor Portuguese:
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alfa-Manosidase
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Synonyms English:
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LAMAN
Neutral alpha-Mannosidase
alpha Mannosidase B
alpha-D-Mannosidase
alpha-D-Mannoside Mannohydrolase
Lysosomal alpha Mannosidase
Mannohydrolase, alpha-D-Mannoside
Mannosidase B, alpha
Neutral alpha Mannosidase
alpha D Mannosidase
alpha D Mannoside Mannohydrolase
alpha Mannosidase
alpha-Mannosidase, Lysosomal
alpha-Mannosidase, Neutral
Lysosomal alpha-Mannosidase
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Tree Number:
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D08.811.277.450.625.500
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Definition English:
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An enzyme that catalyzes the HYDROLYSIS of terminal, non-reducing alpha-D-mannose residues in alpha-D-mannosides. The enzyme plays a role in the processing of newly formed N-glycans and in degradation of mature GLYCOPROTEINS. There are multiple isoforms of alpha-mannosidase, each having its own specific cellular location and pH optimum. Defects in the lysosomal form of the enzyme results in a buildup of mannoside intermediate metabolites and the disease ALPHA-MANNOSIDOSIS. |
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Indexing Annotation English:
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/DEFIC: consider also ALPHA-MANNOSIDOSIS
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See Related English:
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alpha-Mannosidosis
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History Note English:
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2004; use ALPHA-MANNOSIDASE (NM) 1980-2003
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Allowable Qualifiers English:
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Record Number:
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38163
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Unique Identifier:
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D043323
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Occurrence in VHL:
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Similar:
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DeCS CID-10 SciELO LILACS LIS
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