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ZINOSTATIN
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DeCS
Descriptor
English
:
Zinostatin
Descriptor
Spanish
:
Cinostatina
Descriptor
Portuguese
:
Zinostatina
Synonyms
English
:
Neocarzinostatin
Tree Number:
D02.455.326.271.244.500
D02.455.326.397.662.500.500.500
Definition
English
:
An enediyne that alkylates DNA and RNA like
MITOMYCIN
does, so it is cytotoxic.
Pharmacological Action:
Antibiotics, Antineoplastic
Cytotoxins
Nucleic Acid Synthesis Inhibitors
History Note
English
:
93; was NEOCARZINOSTATIN 1975-92 (see under ANTIBIOTICS, ANTINEOPLASTIC 1975-90)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
EC
economics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
30876
Unique Identifier:
D009353
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS