Search on: TACRINE 
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Descriptor English:   Tacrine 
Descriptor Spanish:   Tacrina 
Descriptor Portuguese:   Tacrina 
Synonyms English:   1,2,3,4-Tetrahydro-9-acridinamine
1,2,3,4-Tetrahydroaminoacridine
9-Amino-1,2,3,4-Tetrahydroacridine
Cognex
Horizon Brand of Tacrine Hydrochloride
OTL Pharm Brand of Tacrine Hydrochloride
Parke Davis Brand of Tacrine Hydrochloride
Romotal
THA
Tacrine Hydrochloride
Tenakrin
Woods Brand of Tacrine Hydrochloride
Tetrahydroaminoacridine  
Tree Number:   D03.633.300.046.250.900
Definition English:   A cholinesterase inhibitor that crosses the blood-brain barrier. Tacrine has been used to counter the effects of muscle relaxants, as a respiratory stimulant, and in the treatment of Alzheimer's disease and other central nervous system disorders. 
Pharmacological Action:   Cholinesterase Inhibitors
Nootropic Agents
Parasympathomimetics
 
History Note English:   91(75); was see under AMINOACRIDINES 1984-90; was see under ACRIDINES 1975-83 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AA analogs & derivatives
AN analysis AI antagonists & inhibitors
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
EC economics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UR urine
Record Number:   13996 
Unique Identifier:   D013619 

Occurrence in VHL: 		 

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