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PLASMIN
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DeCS
Descriptor
English
:
Fibrinolysin
Descriptor
Spanish
:
Fibrinolisina
Descriptor
Portuguese
:
Fibrinolisina
Synonyms
English
:
Fibrogammin
Glu-Plasmin
Protease F
Thrombolysin
Glu Plasmin
Plasmin
Tree Number:
D08.811.277.656.300.760.330
D08.811.277.656.959.350.330
Definition
English
:
A product of the lysis of
plasminogen
(profibrinolysin) by
PLASMINOGEN activators
. It is composed of two polypeptide chains, light (B) and heavy (A), with a
molecular weight
of 75,000. It is the major proteolytic enzyme involved in blood
clot retraction
or the lysis of
fibrin
and quickly inactivated by antiplasmins.
Pharmacological Action:
Fibrinolytic Agents
History Note
English
:
2010, 1963-1992;
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
30897
Unique Identifier:
D005341
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
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