Search on:
PINDAC
Descriptors Found:
1
Displaying:
1 .. 1
1 / 1
DeCS
Descriptor
English
:
Pinacidil
Descriptor
Spanish
:
Pinacidilo
Descriptor
Portuguese
:
Pinacidil
Synonyms
English
:
Pinacidil Anhydrous
Pindac
Anhydrous, Pinacidil
Tree Number:
D02.078.370.729
Definition
English
:
A
guanidine
that opens
POTASSIUM CHANNELS
producing direct peripheral vasodilatation of the
ARTERIOLES
. It reduces
BLOOD PRESSURE
and peripheral resistance and produces fluid retention. (Martindale The Extra Pharmacopoeia, 31st ed)
Pharmacological Action:
Antihypertensive Agents
Membrane Transport Modulators
Vasodilator Agents
History Note
English
:
99; use PINACIDIL (NM) 1980-98
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
EC
economics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
33787
Unique Identifier:
D020110
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS