Search on: NOMIFENSIN 
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Descriptor English:   Nomifensine 
Descriptor Spanish:   Nomifensina 
Descriptor Portuguese:   Nomifensina 
Synonyms English:   Hoe-984
Linamiphen
Merital
Nomifensin
Nomifensine Maleate
Nomifensine Maleate (1:1)
Hoe 984
Hoe984
Maleate, Nomifensine  
Tree Number:   D03.633.100.531.535
Definition English:   An isoquinoline derivative that prevents dopamine reuptake into synaptosomes. The maleate was formerly used in the treatment of depression. It was withdrawn worldwide in 1986 due to the risk of acute hemolytic anemia with intravascular hemolysis resulting from its use. In some cases, renal failure also developed. (From Martindale, The Extra Pharmacopoeia, 30th ed, p266) 
Pharmacological Action:   Dopamine Uptake Inhibitors
 
History Note English:   86(78); was see under ISOQUINOLINES 1978-85 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AA analogs & derivatives
AN analysis AI antagonists & inhibitors
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
EC economics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UR urine
Record Number:   24345 
Unique Identifier:   D009627 

Occurrence in VHL:
 

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