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NKH-477
Descriptors Found:
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DeCS
Descriptor
English
:
Colforsin
Descriptor
Spanish
:
Colforsina
Descriptor
Portuguese
:
Colforsina
Synonyms
English
:
N,N-Dimethyl-beta-alanine-5-(acetyloxy)-3-ethenyldodecahydro-10,10b-dihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-1H-naphtho(2,1-b)pyran-6-yl Ester HCl
NKH 477
NKH-477
NKH477
Coleonol
Forskolin
Tree Number:
D02.455.849.291.300
Definition
English
:
Potent activator of the adenylate cyclase system and the biosynthesis of
cyclic AMP
. From the plant
COLEUS
FORSKOHLII. Has antihypertensive, positive inotropic,
platelet aggregation
inhibitory, and smooth muscle relaxant activities; also lowers
intraocular pressure
and promotes release of
hormones
from the
pituitary gland.
Pharmacological Action:
Adjuvants, Immunologic
Bronchodilator Agents
Cardiotonic Agents
Vasodilator Agents
History Note
English
:
2014(1986)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
EC
economics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
19578
Unique Identifier:
D005576
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS