Search on: METALLOPROTEASES 
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Descriptor English:   Metalloproteases 
Descriptor Spanish:   Metaloproteasas 
Descriptor Portuguese:   Metaloproteases 
Synonyms English:   Metallopeptidases
Metalloproteinases  
Tree Number:   D08.811.277.656.675
Definition English:   Proteases which use a metal, normally ZINC, in the catalytic mechanism. This group of enzymes is inactivated by metal CHELATORS. 
Indexing Annotation English:   GEN; prefer specifics
History Note English:   2004; use METALLOENDOPEPTIDASES 1988-2003 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   38178 
Unique Identifier:   D045726 

Occurrence in VHL:
 

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