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DeCS
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Descriptor English:
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Lissencephaly
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Descriptor Spanish:
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Lisencefalia
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Descriptor Portuguese:
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Lisencefalia
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Synonyms English:
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Broad Gyri of Cerebrum
Large Gyri of Cerebrum
Lissencephalia
Macrogyria
Agyrias
Lissencephalies
Macrogyrias
Pachygyrias
Agyria
Pachygyria
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Tree Number:
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C10.500.507.450.499
C16.131.666.507.450.499
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Definition English:
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A smooth brain malformation of the CEREBRAL CORTEX resulting from the abnormal location of developing neurons during corticogenesis. It is characterized by an absence of normal convoluted indentations on the surface of the brain (agyria), or fewer and shallower indentations (pachygryia). There is a reduced number of cortical layers, typically 4 instead of 6, resulting in a thickened cortex, and reduced cerebral white matter that is a reversal of the normal ratio of cerebral white matter to cortex. |
Indexing Annotation English:
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note specifics; MICROLISSENCEPHALY see MICROCEPHALY is also available
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History Note English:
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2008
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Allowable Qualifiers English:
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Record Number:
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52594
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Unique Identifier:
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D054082
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Occurrence in VHL:
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Similar:
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DeCS CID-10 SciELO LILACS LIS
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