Search on: LIPOPOLYSACCHARIDES 
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Descriptor English:   Lipopolysaccharides 
Descriptor Spanish:   Lipopolisacáridos 
Descriptor Portuguese:   Lipopolissacarídeos 
Synonyms English:   Lipoglycans  
Tree Number:   D09.400.500
D09.698.718.450
D10.494
D23.050.161.616.525
D23.946.123.329.500
Definition English:   Lipid-containing polysaccharides which are endotoxins and important group-specific antigens. They are often derived from the cell wall of gram-negative bacteria and induce immunoglobulin secretion. The lipopolysaccharide molecule consists of three parts: LIPID A, core polysaccharide, and O-specific chains (O ANTIGENS). When derived from Escherichia coli, lipopolysaccharides serve as polyclonal B-cell mitogens commonly used in laboratory immunology. (From Dorland, 28th ed) 
Indexing Annotation English:   coordinate IM with specific bacterium (IM) if pertinent; DF: LPS
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UR urine
Record Number:   28155 
Unique Identifier:   D008070 

Occurrence in VHL: 		 

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