Search on: LEUPEPTINS 
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Descriptor English:   Leupeptins 
Descriptor Spanish:   Leupeptinas 
Descriptor Portuguese:   Leupeptinas 
Tree Number:   D12.644.456.580
Definition English:   A group of acylated oligopeptides produced by Actinomycetes that function as protease inhibitors. They have been known to inhibit to varying degrees trypsin, plasmin, KALLIKREINS, papain and the cathepsins. 
Indexing Annotation English:   protease inhib
Pharmacological Action:   Protease Inhibitors
 
History Note English:   91(75); was see under OLIGOPEPTIDES 1975-90 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UR urine  
Record Number:   8152 
Unique Identifier:   D007976 

Occurrence in VHL:
 

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