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LACTOSYLCERAMIDES
Descriptors Found:
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DeCS
Descriptor
English
:
Lactosylceramides
Descriptor
Spanish
:
Lactosilceramidos
Descriptor
Portuguese
:
Lactosilceramidas
Synonyms
English
:
Ceramides, Lactosyl
Lactosyl Ceramides
Tree Number:
D02.065.313.612
D09.400.410.420.525.200.612
D10.390.470.675.200.612
D10.570.877.360.612.200.612
Definition
English
:
Glycosphingolipids
which contain as their polar head group a
lactose
moiety bound in glycosidic linkage to the hydroxyl group of ceramide. Their accumulation in
tissue
, due to a defect in lactosylceramide
beta-galactosidase
, is the cause of lactosylceramidosis.
Indexing Annotation
English
:
/biosyn /physiol permitted
History Note
English
:
91(79); was see under GLYCOSPHINGOLIPIDS 1979-90
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
7968
Unique Identifier:
D007790
Occurrence in VHL
:
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DeCS
CID-10
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