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LACTOFERRIN
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DeCS
Descriptor
English
:
Lactoferrin
Descriptor
Spanish
:
Lactoferrina
Descriptor
Portuguese
:
Lactoferrina
Synonyms
English
:
Lactotransferrin
Tree Number:
D08.811.277.656.300.760.471
D08.811.277.656.959.350.471
D12.776.157.427.750.249
D12.776.256.626.816.500.507
D12.776.377.457.507
D12.776.395.507
D12.776.556.579.750.249
Definition
English
:
An iron-binding protein that was originally characterized as a milk protein. It is widely distributed in secretory fluids and is found in the neutrophilic granules of
LEUKOCYTES
. The N-terminal part of
lactoferrin
possesses a
serine
protease which functions to inactivate the TYPE III SECRETION SYSTEM used by
bacteria
to export
virulence
proteins
for host cell invasion.
Pharmacological Action:
Anti-Infective Agents
History Note
English
:
91(73); was see under LACTOGLOBULINS 1973-90
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
7958
Unique Identifier:
D007781
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS