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INDOLIZIDINES
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DeCS
Descriptor
English
:
Indolizidines
Descriptor
Spanish
:
Indolicidinas
Descriptor
Portuguese
:
Indolizidinas
Tree Number:
D03.633.100.496.500
Definition
English
:
Saturated
indolizines
that are fused six and five-membered rings with a
nitrogen
atom at the ring fusion. They are biosynthesized in
PLANTS
by
cyclization
of a
LYSINE
coupled to
ACETYL COENZYME A
. Many of them are naturally occurring
ALKALOIDS.
History Note
English
:
2008
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
EC
economics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
52649
Unique Identifier:
D054836
Occurrence in VHL
:
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