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FURIN
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DeCS
Descriptor
English
:
Furin
Descriptor
Spanish
:
Furina
Descriptor
Portuguese
:
Furina
Synonyms
English
:
Furin Protein
Paired Basic Amino Acid Cleaving Enzyme
SPC1 Proteinase
Processing Enzyme, Dibasic
Dibasic Processing Enzyme
Tree Number:
D08.811.277.656.300.760.353
D08.811.277.656.837.249
D08.811.277.656.959.350.353
Definition
English
:
A proprotein convertase with specificity for the proproteins of PROALBUMIN; COMPLEMENT 3C; and
VON WILLEBRAND FACTOR
. It has specificity for cleavage near paired
ARGININE
residues that are separated by two
amino acids.
History Note
English
:
2004; use FURIN (NM) 1993-2003
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
38168
Unique Identifier:
D045683
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS