Search on: DIZOCILPINE 
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Descriptor English:   Dizocilpine Maleate 
Descriptor Spanish:   Maleato de Dizocilpina 
Descriptor Portuguese:   Maleato de Dizocilpina 
Synonyms English:   MK-801
MK 801
MK801
Dizocilpine  
Tree Number:   D02.455.426.559.847.181.384.380
D04.615.181.384.380
Definition English:   A potent noncompetitive antagonist of the NMDA receptor (RECEPTORS, N-METHYL-D-ASPARTATE) used mainly as a research tool. The drug has been considered for the wide variety of neurodegenerative conditions or disorders in which NMDA receptors may play an important role. Its use has been primarily limited to animal and tissue experiments because of its psychotropic effects. 
Indexing Annotation English:   DF: note short X
Pharmacological Action:   Excitatory Amino Acid Antagonists
Neuroprotective Agents
 
History Note English:   91 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AA analogs & derivatives
AN analysis AI antagonists & inhibitors
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
EC economics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UR urine
Record Number:   28911 
Unique Identifier:   D016291 

Occurrence in VHL:
 

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