Search on: DIMETHYLALLYLTRANSTRANSFERASE 
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Descriptor English:   Dimethylallyltranstransferase 
Descriptor Spanish:   Dimetilaliltranstransferasa 
Descriptor Portuguese:   Dimetilaliltranstransferase 
Synonyms English:   Dolichyl Phosphate Synthetase
Geranylgeranyl Pyrophosphate Synthetase
Nerylpyrophosphate Synthetase
Synthetase, Geranylpyrophosphate
Synthetase, Nerylpyrophosphate
Geranylpyrophosphate Synthetase
Prenyltransferase
Dimethylallyltransferase  
Tree Number:   D08.811.913.225.400
Definition English:   An enzyme that, in the pathway of cholesterol biosynthesis, catalyzes the condensation of isopentenyl pyrophosphate and dimethylallylpyrophosphate to yield pyrophosphate and geranylpyrophosphate. The enzyme then catalyzes the condensation of the latter compound with another molecule of isopentenyl pyrophosphate to yield pyrophosphate and farnesylpyrophosphate. EC 2.5.1.1. 
History Note English:   97; was DIMETHYLALLYLTRANSFERASE 1979-96 (see under TRANSFERASES 1979-90) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   4170 
Unique Identifier:   D004122 

Occurrence in VHL:
 

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