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CYTOLIPINS
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DeCS
Descriptor
English
:
Globosides
Descriptor
Spanish
:
Globósidos
Descriptor
Portuguese
:
Globosídeos
Synonyms
English
:
Lactoneotetraosylceramide
Lacto N neotetraosylceramide
Lacto N tetraosylceramide
Cytolipins
Lacto-N-neotetraosylceramide
Lacto-N-tetraosylceramide
Tree Number:
D02.065.313.425
D09.400.410.420.525.200.425
D10.390.470.675.200.425
D10.570.877.360.612.200.425
Definition
English
:
Glycosphingolipids
containing N-acetylglucosamine (paragloboside) or N-acetylgalactosamine (globoside). Globoside is the P
antigen
on
erythrocytes
and paragloboside is an intermediate in the biosynthesis of erythrocyte blood group ABH and P 1 glycosphingolipid
antigens
. The accumulation of globoside in
tissue
, due to a defect in
hexosaminidases
A and B, is the cause of
Sandhoff disease.
Indexing Annotation
English
:
/biosyn /physiol permitted
History Note
English
:
91(79); was see under GLYCOSPHINGOLIPIDS 1979-90
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
6060
Unique Identifier:
D005915
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS