Search on: CULICININS 
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Descriptor English:   Peptaibols 
Descriptor Spanish:   Peptaiboles 
Descriptor Portuguese:   Peptaibols 
Synonyms English:   Atroviridins
Emerimicin
Emerimicins
Trichorzianines
Alamethicins
Antiamoebins
Chrysospermins
Culicinins
Zervamicins  
Tree Number:   D12.644.504
Definition English:   A group of peptides characterized by length of 1-2 dozen residues with a high proportion of them being non-proteinogenic, notably alpha-aminoisobutyric acid (Aib) and isovaline, and have a C-terminal amino alcohol and N terminal alkyl group. They are found in FUNGI and some are ANTI-INFECTIVE AGENTS. They form channels or pores in target organisms. The term is a contraction of peptide-Aib-alcohol. 
History Note English:   2008; for EMERIMICINS use PEPTIDES 1977-2007 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UR urine  
Record Number:   52785 
Unique Identifier:   D054848 

Occurrence in VHL:
 

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