Search on: CHALONES 
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Descriptor English:   Chalones 
Descriptor Spanish:   Chalonas 
Descriptor Portuguese:   Calônios 
Tree Number:   D12.644.456.270
Definition English:   Peptides that inhibit mitosis (ANTIMITOTICS). During the 1960's the term referred to crude extracts that inhibited cell proliferation; the activity was later attributed to PYROGLUTAMATE type oligopeptides. 
Indexing Annotation English:   do not confuse with CHALCONES
History Note English:   2006, 1969-1992; use GROWTH INHIBITORS 1993-2005 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UR urine  
Record Number:   50818 
Unique Identifier:   D050150 

Occurrence in VHL:
 

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