Search on: CATHEPSIN 
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Descriptor English:   Cathepsins 
Descriptor Spanish:   Catepsinas 
Descriptor Portuguese:   Catepsinas 
Synonyms English:   Cathepsin  
Tree Number:   D08.811.277.656.224
Definition English:   A group of lysosomal proteinases or endopeptidases found in aqueous extracts of a variety of animal tissues. They function optimally within an acidic pH range. The cathepsins occur as a variety of enzyme subtypes including SERINE PROTEASES; ASPARTIC PROTEINASES; and CYSTEINE PROTEASES. 
Indexing Annotation English:   note specifics
History Note English:   79; was CATHEPSIN 1963-78 (Prov 1963-64) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   2445 
Unique Identifier:   D002403 

Occurrence in VHL:
 

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