Search on: CP-10,188 
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Descriptor English:   Fenclonine 
Descriptor Spanish:   Fenclonina 
Descriptor Portuguese:   Fenclonina 
Synonyms English:   CP-10,188
DL-3-(4-Chlorophenyl)alanine
Fenclonin
Fenclonine (L)-Isomer
Fenclonine Hydrobromide
Fenclonine Hydrochloride
Fenclonine, (D)-Isomer
Hydrobromide, Fenclonine
Hydrochloride, Fenclonine
para Chlorophenylalanine
p-Chlorophenylalanine
para-Chlorophenylalanine  
Tree Number:   D12.125.072.050.685.440
Definition English:   A selective and irreversible inhibitor of tryptophan hydroxylase, a rate-limiting enzyme in the biosynthesis of serotonin (5-HYDROXYTRYPTAMINE). Fenclonine acts pharmacologically to deplete endogenous levels of serotonin. 
Pharmacological Action:   Enzyme Inhibitors
Serotonin Antagonists
 
History Note English:   93(71) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AA analogs & derivatives
AN analysis AI antagonists & inhibitors
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
EC economics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UR urine
Record Number:   30927 
Unique Identifier:   D010134 

Occurrence in VHL: 		 

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