Search on: ANGIOSTATINS 
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Descriptor English:   Angiostatins 
Descriptor Spanish:   Angiostatinas 
Descriptor Portuguese:   Angiostatinas 
Synonyms English:   Angiostatin  
Tree Number:   D08.622.610.500
D12.644.276.100.450.500
D12.776.124.790.223.580.500
D12.776.377.715.182.580.500
D12.776.467.100.450.500
D23.529.100.450.500
Definition English:   Circulating 38-kDa proteins that are internal peptide fragments of PLASMINOGEN. The name derives from the fact that they are potent ANGIOGENESIS INHIBITORS. Angiostatins contain four KRINGLE DOMAINS which are associated with their potent angiostatic activity. 
Pharmacological Action:   Angiogenesis Inhibitors
Antineoplastic Agents
 
History Note English:   2004; use ANGIOSTATINS (NM) 1994-2003 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UR urine
Record Number:   38124 
Unique Identifier:   D043168 

Occurrence in VHL: 		 

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