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ANGIOPOIETIN-2
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DeCS
Descriptor
English
:
Angiopoietin-2
Descriptor
Spanish
:
Angiopoyetina 2
Descriptor
Portuguese
:
Angiopoietina-2
Synonyms
English
:
Angiopoietin 2
Tree Number:
D12.644.276.100.100.200
D12.776.467.100.100.200
D23.529.100.100.200
Definition
English
:
An angiopoietin that is closely related to
ANGIOPOIETIN-1
. It binds to the TIE-2 RECEPTOR without receptor stimulation and antagonizes the effect of
ANGIOPOIETIN-1
. However its antagonistic effect may be limited to cell receptors that occur within the vasculature.
Angiopoietin-2
may therefore play a role in
down-regulation
of BLOOD VESSEL branching and sprouting.
History Note
English
:
2004; use ANGIOPOIETIN-2 (NM) 1997-2003
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
38239
Unique Identifier:
D042702
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
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