Search on:
2-(4'-THIAZOLYL)BENZIMIDAZOLE
Descriptors Found:
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DeCS
Descriptor
English
:
Thiabendazole
Descriptor
Spanish
:
Tiabendazol
Descriptor
Portuguese
:
Tiabendazol
Synonyms
English
:
2-(4'-Thiazolyl)Benzimidazole
Mintesol
Mintezol
Omnizole
Thibendole
Tiabendazol
Tree Number:
D02.886.675.840
D03.383.129.708.824
D03.633.100.103.850
Definition
English
:
2-Substituted benzimidazole first introduced in 1962. It is active against a variety of nematodes and is the drug of choice for
STRONGYLOIDIASIS
. It has
CENTRAL NERVOUS SYSTEM
side effects and hepatototoxic potential. (From Smith and Reynard, Textbook of
Pharmacology
, 1992, p919)
Pharmacological Action:
Anthelmintics
History Note
English
:
65(63)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
EC
economics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
14204
Unique Identifier:
D013827
Occurrence in VHL
:
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