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BETA-LACTAMS
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DeCS
Descriptor
English
:
beta-Lactams
Descriptor
Spanish
:
beta-Lactamas
Descriptor
Portuguese
:
beta-Lactamas
Synonyms
English
:
4-Thia-1-Azabicyclo(3.2.0)Heptanes
4-Thia-1-Azabicyclo(4.2.0)Octanes
beta Lactams
Tree Number:
D02.065.589.099
D02.886.108
D03.633.100.300
Definition
English
:
Four-membered cyclic
AMIDES
, best known for the
PENICILLINS
based on a bicyclo-thiazolidine, as well as the
CEPHALOSPORINS
based on a bicyclo-thiazine, and including monocyclic
MONOBACTAMS
. The
BETA-LACTAMASES
hydrolyze the beta lactam ring,
accounting
for
BETA-LACTAM RESISTANCE
of infective
bacteria.
Pharmacological Action:
Anti-Bacterial Agents
History Note
English
:
2005; use LACTAMS 1996-2004
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
EC
economics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
38654
Unique Identifier:
D047090
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
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