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MODULATIONS, ANTIGENIC
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DeCS
Descriptor
English
:
Antigenic Modulation
Descriptor
Spanish
:
Modulación Antigénica
Descriptor
Portuguese
:
Modulação Antigênica
Synonyms
English
:
Antigenic Modulations
Modulation, Antigenic
Modulations, Antigenic
Tree Number:
G12.122.140
Definition
English
:
Loss of detectable
antigen
from the surface of a cell after incubation with
antibodies
. This is one method in which some tumors escape
detection
by the
immune system
.
Antigenic modulation
of target
antigens
also reduces the therapeutic
effectiveness
of treatment by
monoclonal antibodies.
History Note
English
:
92
Allowable Qualifiers
English
:
DE
drug effects
ES
ethics
GE
genetics
IM
immunology
PH
physiology
RE
radiation effects
Record Number:
30261
Unique Identifier:
D016525
Occurrence in VHL
:
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