|
1 / 1
|
DeCS
|
|
 |
|
Descriptor Inglés:
|
|
Phosphatidylinositol-3,4,5-Trisphosphate 5-Phosphatases
|
|
Descriptor Español:
|
|
Fosfatidilinositol-3,4,5-Trifosfato 5-Fosfatasas
|
|
Descriptor Portugués:
|
|
Fosfatidilinositol-3,4,5-Trifosfato 5-Fosfatases
|
|
Sinónimos Inglés:
|
|
SHIP Phosphatases
Src Homology 2 Domain-Containing Inositol Phosphatases
Phosphatases, SHIP
Src Homology 2 Domain Containing Inositol Phosphatases
|
|
Categoría:
|
|
D08.811.277.352.650.624.750
|
|
Definición Inglés:
|
|
Phosphoinositide phosphatases that catalyze the dephosphorylation (hydrolysis) of phosphatidylinositol-3,4,5-trisphosphate (PtdIns(3,4,5)P(3)) to produce PtdIns(3,4)P(2), which negatively regulates the PI3K ( 3-PHOSPHOINOSITIDE-DEPENDENT PROTEIN KINASES) pathways. They contain an SH2 DOMAIN and STERILE ALPHA MOTIF and have important functions in regulating the immune response and other cellular processes in vertebrates. |
|
Nota Histórica Inglés:
|
|
2017
|
|
Calificadores Permitidos Inglés:
|
|
|
|
Número del Registro:
|
|
56477
|
|
Identificador Único:
|
|
D000072183
|
Ocurrencia en la BVS:
|
|
|
Similar:
|
|
DeCS CID-10 SciELO LILACS LIS
|