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DeCS
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Descriptor Inglés:
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NLR Family, Pyrin Domain-Containing 3 Protein
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Descriptor Español:
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Proteína con Dominio Pirina 3 de la Familia NLR
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Descriptor Portugués:
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Proteína 3 que Contém Domínio de Pirina da Família NLR
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Sinónimos Inglés:
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Cold Autoinflammatory Syndrome 1 Protein
NACHT, LRR and PYD Domains-Containing Protein 3
NLRP3 Protein
NACHT, LRR and PYD Domains Containing Protein 3
NLR Family, Pyrin Domain Containing 3 Protein
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Categoría:
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D12.644.360.539.250
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Definición Inglés:
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An NLR protein that contains an N-terminal PYRIN DOMAIN and ATP-binding site and 9 C-terminal LEUCINE-rich repeats; it is expressed primarily by MACROPHAGES. It is a core component of the INFLAMMASOME and directs its assembly in response to pathogen infection and damage-associated stimuli. Mutations in the NLRP3 gene are associated with FAMILIAL COLD AUTOINFLAMMATORY SYNDROME. |
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Nota Histórica Inglés:
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2017
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Calificadores Permitidos Inglés:
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Número del Registro:
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56550
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Identificador Único:
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D000071199
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Ocurrencia en la BVS:
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Similar:
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DeCS CID-10 SciELO LILACS LIS
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