Expresión de búsqueda:
MUTL PROTEIN HOMOLOG 1
Descriptores Encontrados:
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DeCS
Descriptor
Inglés
:
MutL Protein Homolog 1
Descriptor
Español
:
Homólogo 1 de la Proteína MutL
Descriptor
Portugués
:
Proteína 1 Homóloga a MutL
Sinónimos
Inglés
:
COCA2 Protein
Colon Cancer, Nonpolyposis Type 2 Protein
MLH1 Protein
MutL Homolog 1
Categoría:
D08.811.074.766.500
D08.811.277.040.025.215.500
D12.776.260.540.500
Definición
Inglés
:
Eukaryotic homolog of the bacterial MutL
DNA MISMATCH REPAIR
protein. It heterodimerizes with
MISMATCH REPAIR ENDONUCLEASE PMS2
to form MutL alpha, which is recruited to DNA mismatch sites by the
MUTS DNA MISMATCH-BINDING PROTEIN
.
Mutations
in the human MLH1 gene are associated with
COLORECTAL NEOPLASMS
, HEREDITARY NONPOLYPOSIS.
Nota Histórica
Inglés
:
2017
Calificadores Permitidos
Inglés
:
AD
administration & dosage
AE
adverse effects
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Número del Registro:
56467
Identificador Único:
D000070957
Ocurrencia en la BVS
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS