Expresión de búsqueda: DNA LIGASE ATP 
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Descriptor Inglés:   DNA Ligase ATP 
Descriptor Español:   ADN Ligasa (ATP) 
Descriptor Portugués:   DNA Ligase Dependente de ATP 
Sinónimos Inglés:   DNA Ligase I
DNA Ligase II
DNA Ligase III
DNA Ligase IV
DNA Ligases, ATP-Dependent
Polydeoxyribonucleotide Synthase ATP
ATP, DNA Ligase
ATP, Polydeoxyribonucleotide Synthase
ATP-Dependent DNA Ligases
DNA Ligases, ATP Dependent
Ligase ATP, DNA
Ligase I, DNA
Ligase II, DNA
Ligase III, DNA
Ligase IV, DNA
Ligases, ATP-Dependent DNA
Synthase ATP, Polydeoxyribonucleotide  
Categoría:   D08.811.074.500.500
D08.811.464.754.600.500
Definición Inglés:   ATP-dependent cellular enzyme which catalyzes DNA replication, repair and recombination through formation of internucleotide ester bonds between phosphate and deoxyribose moieties. Vertebrate cells encode three well-characterized DNA ligases, DNA ligase I, III and IV, all of which are related in structure and sequence. DNA ligases either require ATP or NAD. However, archaebacterial, viral, and some eubacterial DNA ligases are ATP-dependent. 
Nota Histórica Inglés:   2017 (1986) 
Calificadores Permitidos Inglés:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Número del Registro:   56464 
Identificador Único:   D000072481 

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