Expresión de búsqueda: AUTOPHAGY-RELATED PROTEIN 5 
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Descriptor Inglés:   Autophagy-Related Protein 5 
Descriptor Español:   Proteína 5 Relacionada con la Autofagia 
Descriptor Portugués:   Proteína 5 Relacionada à Autofagia 
Sinónimos Inglés:   ATG-5 Protein
ATG5 Protein
Apoptosis-Specific Protein
Autophagy Protein-5
Autophagy-Related 5 Protein
ATG 5 Protein
Apoptosis Specific Protein
Autophagy Protein 5
Autophagy Related 5 Protein
Autophagy Related Protein 5  
Categoría:   D12.776.094.250
Definición Inglés:   An autophagy-related protein that functions in AUTOPHAGOSOME biogenesis. It is conjugated to the ATG12 PROTEIN via a process that is similar to UBIQUITINATION and involves the ATG7 PROTEIN and ATG10 enzyme. The ATG12-ATG5 conjugate acts as an E3 UBIQUITIN LIGASE-like enzyme and is required for the localization of ATG8 PROTEINS to AUTOPHAGOSOME vesicle membranes and modification of membrane lipids. 
Nota Histórica Inglés:   2017 
Calificadores Permitidos Inglés:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Número del Registro:   56557 
Identificador Único:   D000071187 

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