Pesquisa sobre: GLUTAREDOXINS 
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Descritor Inglês:   Glutaredoxins 
Descritor Espanhol:   Glutarredoxinas 
Descritor Português:   Glutarredoxinas 
Sinônimos Inglês:   Glutaredoxin 1
Glutaredoxin 2
Glutaredoxin 3
Glutaredoxin 5
TTase-1
Thioltransferase
Thioltransferase-1
TTase 1
Thioltransferase 1
Glutaredoxin  
Categoria:   D08.811.682.667.084
Definição Inglês:   A family of thioltransferases that contain two active site CYSTEINE residues, which either form a disulfide (oxidized form) or a dithiol (reduced form). They function as an electron carrier in the GLUTHIONE-dependent synthesis of deoxyribonucleotides by RIBONUCLEOTIDE REDUCTASES and may play a role in the deglutathionylation of protein thiols. The oxidized forms of glutaredoxins are directly reduced by the GLUTATHIONE. 
Nota Histórica Inglês:   2008(1980); use PROTEINS 1979 
Qualificadores Permitidos Inglês:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Número do Registro:   52721 
Identificador Único:   D054477 

Ocorrência na BVS:
 

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