Search on: SPLA2-X 
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Descriptor English:   Group X Phospholipases A2 
Descriptor Spanish:   Fosfolipasas A2 Grupo X 
Descriptor Portuguese:   Fosfolipases A2 do Grupo X 
Synonyms English:   GX sPLA(2)
Group X Secretory Phospholipase A(2)
Group X Secretory Phospholipase A2
Phospholipase A2, Group X
sPLA(2)-X
sPLA2-X
Phospholipases A2, Group X  
Tree Number:   D08.811.277.352.100.680.750.937.750.887
Definition English:   A secreted phospholipase A2 subtype that contains a interfacial-binding region with specificity for PHOSPHATIDYLCHOLINE. This enzyme group may play a role in eliciting ARACHIDONIC ACID release from intact cellular membranes and from LOW DENSITY LIPOPROTEINS. Members of this group bind specifically to PHOSPHOLIPASE A2 RECEPTORS. 
Indexing Annotation English:   /antag: coordinate with PHOSPHOLIPASE A2 INHIBITORS
History Note English:   2008(2002) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   52674 
Unique Identifier:   D054509 

Occurrence in VHL:
 

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