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TUBULIN
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DeCS
Descriptor
English
:
Tubulin
Descriptor
Spanish
:
Tubulina (Proteína)
Descriptor
Portuguese
:
Tubulina (Proteína)
Synonyms
English
:
alpha-Tubulin
beta-Tubulin
delta-Tubulin
epsilon-Tubulin
gamma-Tubulin
alpha Tubulin
beta Tubulin
delta Tubulin
epsilon Tubulin
gamma Tubulin
Tree Number:
D05.750.078.734.800
D12.776.220.600.800
D12.776.631.920
Definition
English
:
A
microtubule
subunit protein found in large quantities in mammalian brain. It has also been isolated from SPERM
FLAGELLUM
; CILIA; and other sources. Structurally, the protein is a dimer with a
molecular weight
of approximately 120,000 and a
sedimentation
coefficient of 5.8S. It binds to
COLCHICINE
;
VINCRISTINE
; and
VINBLASTINE.
Entry Combination - descr/qualif
English
:
Tubulin
/
antagonists & inhibitors
use
Tubulin Modulators
History Note
English
:
80(75); was see under GLYCOPROTEINS 1975-79
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
14806
Unique Identifier:
D014404
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS