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SAQUINAVIR
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DeCS
Descriptor
English
:
Saquinavir
Descriptor
Spanish
:
Saquinavir
Descriptor
Portuguese
:
Saquinavir
Synonyms
English
:
Invirase
Ro 31-8959
Saquinavir Mesylate
Saquinavir Monomethanesulfonate
Saquinivir
Monomethanesulfonate, Saquinavir
Ro 31 8959
Ro 318959
Tree Number:
D03.633.100.531.770
D03.633.100.810.900
Definition
English
:
An
HIV protease
inhibitor which acts as an analog of an
HIV protease
cleavage site. It is a highly specific inhibitor of HIV-1 and HIV-2 proteases, and also inhibits
CYTOCHROME P-450 CYP3A.
Pharmacological Action:
Cytochrome P-450 CYP3A Inhibitors
HIV Protease Inhibitors
History Note
English
:
97; was SAQUINAVIR (NM) 1990-96
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
EC
economics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
32996
Unique Identifier:
D019258
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
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