Search on: PLECTIN 
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Descriptor English:   Plectin 
Descriptor Spanish:   Plectina 
Descriptor Portuguese:   Plectina 
Synonyms English:   500-kDa HD1 Protein
Hemidesmosomal Protein HD1
500 kDa HD1 Protein
HD1 Protein, 500-kDa
HD1, Hemidesmosomal Protein  
Tree Number:   D12.776.220.790.750
D12.776.744.736
Definition English:   A cytoskeletal linker protein with a molecular weight of greater than 500 kDa. It binds INTERMEDIATE FILAMENTS; MICROTUBULES; and ACTIN CYTOSKELETON and plays a central role in the organization and stability of the CYTOSKELETON. Plectin is phosphorylated by CALMODULIN KINASE; PROTEIN KINASE A; and PROTEIN KINASE C. 
History Note English:   2006(1982) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   50941 
Unique Identifier:   D051190 

Occurrence in VHL:
 

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