Search on: MOLINDONE 
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Descriptor English:   Molindone 
Descriptor Spanish:   Molindona 
Descriptor Portuguese:   Molindona 
Synonyms English:   Endo Brand of Molindone Hydrochloride
Moban
Molindone Hydrochloride
Molindone Monohydrochloride
Hydrochloride, Molindone
Monohydrochloride, Molindone  
Tree Number:   D03.633.100.473.629
Definition English:   An indole derivative effective in schizophrenia and other psychoses and possibly useful in the treatment of the aggressive type of undersocialized conduct disorder. Molindone has much lower affinity for D2 receptors than most antipsychotic agents and has a relatively low affinity for D1 receptors. It has only low to moderate affinity for cholinergic and alpha-adrenergic receptors. Some electrophysiologic data from animals indicate that molindone has certain characteristics that resemble those of CLOZAPINE. (From AMA Drug Evaluations Annual, 1994, p283) 
Pharmacological Action:   Antipsychotic Agents
 
History Note English:   91(72); was see under INDOLES 1972-90 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AA analogs & derivatives
AN analysis AI antagonists & inhibitors
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
EC economics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UR urine
Record Number:   9160 
Unique Identifier:   D008972 

Occurrence in VHL:
 

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