Search on: MECHLORETHAMINE 
Descriptors Found: 1
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Descriptor English:   Mechlorethamine 
Descriptor Spanish:   Mecloretamina 
Descriptor Portuguese:   Mecloretamina 
Synonyms English:   Bis(2-chloroethyl)methylamine
Caryolysine
Cloramin
Embichin
Mechlorethamine Hydrochloride
Mechlorethamine Hydrochloride N-Oxide
Mechlorethamine N-Oxide
Methylchlorethamine
Mitomen
Mustargen
NSC-10107
NSC-762
Nitrogranulogen
Nitromin
Hydrochloride N-Oxide, Mechlorethamine
Hydrochloride, Mechlorethamine
Mechlorethamine Hydrochloride N Oxide
Mechlorethamine N Oxide
N-Oxide, Mechlorethamine Hydrochloride
N-Oxide, Nitrogen Mustard
NSC 10107
NSC 762
NSC10107
NSC762
Nitrogen Mustard N Oxide
Chlorethazine
Chlormethine
Mechlorethamine Oxide
Mustine
Nitrogen Mustard
Nitrogen Mustard N-Oxide  
Tree Number:   D02.455.526.728.650.529
Definition English:   A biologic alkylating agent that exerts its cytotoxic effects by forming DNA ADDUCTS and DNA interstrand crosslinks, thereby inhibiting rapidly proliferating cells. The hydrochloride is an antineoplastic agent used to treat HODGKIN DISEASE and LYMPHOMA. 
Pharmacological Action:   Alkylating Agents
Antineoplastic Agents, Alkylating
Chemical Warfare Agents
Irritants
 
History Note English:   MECHLORETHAMINE OXIDE was heading 1963-79; NITROGEN MUSTARD N-OXIDE was NITROGEN MUSTARD N-OXIDE (NM) 1984-91 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AA analogs & derivatives
AN analysis AI antagonists & inhibitors
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
EC economics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UR urine
Record Number:   8635 
Unique Identifier:   D008466 

Occurrence in VHL:
 

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