Search on: ISOMEROREDUCTASE 
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Descriptor English:   Ketol-Acid Reductoisomerase 
Descriptor Spanish:   Cetoácido Reductoisomerasa 
Descriptor Portuguese:   Cetol-Ácido Redutoisomerase 
Synonyms English:   Acetohydroxy Acid Isomeroreductase
Alpha-Acetohydroxyacid Isomeroreductase
Dihydroxyisovalerate Dehydrogenase (Isomerizing)
Hydroxyacid Reductoisomerase
Isomeroreductase
Acid Isomeroreductase, Acetohydroxy
Alpha Acetohydroxyacid Isomeroreductase
Isomeroreductase, Acetohydroxy Acid
Isomeroreductase, Alpha-Acetohydroxyacid
Ketol Acid Reductoisomerase
Reductoisomerase, Hydroxyacid
Reductoisomerase, Ketol-Acid  
Tree Number:   D08.811.682.047.820.487
Definition English:   An enzyme that catalyzes the oxidation of (R)-2,3-dihydroxy-3-methylbutanoate to (S)-2-hydroxy-2-methyl-3-oxobutanoate in the presence of NADP. It is involved in the biosynthesis of VALINE; LEUCINE; ISOLEUCINE; pentothenate and COENZYME A. This enzyme was formerly classified as EC 1.1.1.89. 
History Note English:   2006(1980); use VALERATES 1970-1979 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   50599 
Unique Identifier:   D050540 

Occurrence in VHL:
 

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