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INTERFERON
Descriptors Found:
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DeCS
Descriptor
English
:
Interferons
Descriptor
Spanish
:
Interferones
Descriptor
Portuguese
:
Interferons
Synonyms
English
:
Interferon
Tree Number:
D12.644.276.374.440
D12.776.467.374.440
D23.529.374.440
Definition
English
:
Proteins
secreted by
vertebrate
cells in response to a wide variety of inducers. They confer resistance against many different
viruses
, inhibit proliferation of normal and malignant cells, impede multiplication of intracellular
parasites
, enhance macrophage and
granulocyte
phagocytosis
, augment natural killer cell activity, and show several other immunomodulatory functions.
Indexing Annotation
English
:
"stimulators" or "inducers" =
INTERFERON INDUCERS
Pharmacological Action:
Antineoplastic Agents
Antiviral Agents
See Related
English
:
Receptors, Interferon
History Note
English
:
83; was INTERFERON 1963-82
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
29469
Unique Identifier:
D007372
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS