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Descriptor English:   Intercalating Agents 
Descriptor Spanish:   Sustancias Intercalantes 
Descriptor Portuguese:   Substāncias Intercalantes 
Synonyms English:   Intercalating Ligands
Intercalative Compounds
Agents, Intercalating
Compounds, Intercalative
Ligands, Intercalating
Intercalators  
Tree Number:   D27.720.470.410.360
Definition English:   Agents that are capable of inserting themselves between the successive bases in DNA, thus kinking, uncoiling or otherwise deforming it and therefore preventing its proper functioning. They are used in the study of DNA. 
Indexing Annotation English:   agents "capable of inserting themselves ... between the successive bases in DNA"; used in DNA studies; D25-26 qualif
History Note English:   80 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis CS chemical synthesis
CH chemistry CL classification
CT contraindications EC economics
HI history IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity  
Record Number:   7532 
Unique Identifier:   D007364 

Occurrence in VHL:
 

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