Search on: INFLAMMASOMES 
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Descriptor English:   Inflammasomes 
Descriptor Spanish:   Inflamasomas 
Descriptor Portuguese:   Inflamassomos 
Synonyms English:   Inflammasome
Pyroptosome
Pyroptosomes  
Tree Number:   D05.500.224
Definition English:   Multiprotein complexes that mediate the activation of CASPASE-1. Dysregulation of inflammasomes has also been linked to a number of autoinflammatory and autoimmune disorders. 
See Related English:   Immunity, Innate
Inflammation Mediators
 
History Note English:   2011 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   54035 
Unique Identifier:   D058847 

Occurrence in VHL:
 

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