Search on: IMMUNORADIOTHERAPIES 
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Descriptor English:   Radioimmunotherapy 
Descriptor Spanish:   Radioinmunoterapia 
Descriptor Portuguese:   Radioimunoterapia 
Synonyms English:   Immunoradiotherapy
Immunoradiotherapies
Radioimmunotherapies  
Tree Number:   E02.095.465.425.750
E02.186.750
E02.815.520
Definition English:   Radiotherapy where cytotoxic radionuclides are linked to antibodies in order to deliver toxins directly to tumor targets. Therapy with targeted radiation rather than antibody-targeted toxins (IMMUNOTOXINS) has the advantage that adjacent tumor cells, which lack the appropriate antigenic determinants, can be destroyed by radiation cross-fire. Radioimmunotherapy is sometimes called targeted radiotherapy, but this latter term can also refer to radionuclides linked to non-immune molecules (see RADIOTHERAPY). 
Indexing Annotation English:   radiother by cytotoxic radioisotopes linked to antibodies: read MeSH definition; do not use /util except by MeSH definition; coord IM with disease /radiother (IM)
History Note English:   92 
Allowable Qualifiers English:  
AE adverse effects CL classification
CT contraindications EC economics
ES ethics HI history
IS instrumentation MT methods
MO mortality NU nursing
PX psychology ST standards
SN statistics & numerical data TD trends
UT utilization VE veterinary
Record Number:   29854 
Unique Identifier:   D016499 

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