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Descriptor English:   Levodopa 
Descriptor Spanish:   Levodopa 
Descriptor Portuguese:   Levodopa 
Synonyms English:   3-Hydroxy-L-tyrosine
Dopaflex
Dopar
L-3,4-Dihydroxyphenylalanine
Larodopa
Levopa
3 Hydroxy L tyrosine
L 3,4 Dihydroxyphenylalanine
L Dopa
L-Dopa  
Tree Number:   D02.092.311.200.480
D12.125.072.050.685.400.500
D12.125.072.050.875.130.500
Definition English:   The naturally occurring form of DIHYDROXYPHENYLALANINE and the immediate precursor of DOPAMINE. Unlike dopamine itself, it can be taken orally and crosses the blood-brain barrier. It is rapidly taken up by dopaminergic neurons and converted to DOPAMINE. It is used for the treatment of PARKINSONIAN DISORDERS and is usually given with agents that inhibit its conversion to dopamine outside of the central nervous system. 
Pharmacological Action:   Antiparkinson Agents
Dopamine Agents
 
See Related English:   Dopamine
 
History Note English:   75; was see DOPA 1972-74 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AA analogs & derivatives
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UR urine  
Record Number:   24230 
Unique Identifier:   D007980 

Occurrence in VHL:
 

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