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DeCS
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Descriptor English:
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Disulfiram
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Descriptor Spanish:
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Disulfiram
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Descriptor Portuguese:
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Dissulfiram
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Synonyms English:
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Alcophobin
Antabus
Antabuse
Anticol
Bis(diethylthiocarbamoyl) Disulfide
Dicupral
Esperal
Tetraethylthioperoxydicarbonic Diamide, ((H2N)C(S))2S2
Teturam
Disulfide, Tetraethylthiuram
Tetraethylthiuram Disulfide
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Tree Number:
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D02.241.081.251.869.220.250
D02.886.520.150.175
D02.886.706.200.200
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Definition English:
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A carbamate derivative used as an alcohol deterrent. It is a relatively nontoxic substance when administered alone, but markedly alters the intermediary metabolism of alcohol. When alcohol is ingested after administration of disulfiram, blood acetaldehyde concentrations are increased, followed by flushing, systemic vasodilation, respiratory difficulties, nausea, hypotension, and other symptoms (acetaldehyde syndrome). It acts by inhibiting aldehyde dehydrogenase. |
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Pharmacological Action:
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Acetaldehyde Dehydrogenase Inhibitors
Alcohol Deterrents
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Allowable Qualifiers English:
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Record Number:
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4282
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Unique Identifier:
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D004221
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Occurrence in VHL:
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Similar:
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DeCS CID-10 SciELO LILACS LIS
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